Secondary osteoarthritis – Special features in Rheumatoid Arthritis
Rheumatoid Arthritis and Osteoarthritis: Why Hips and Knees are Particularly at Risk

Many people with rheumatism know: It rarely stays a pure inflammation of the joints. Often, over the years, a secondary osteoarthritis – also a joint wear, caused by the Rheumatoid arthritis is triggered. Especially the large joints such as hip and knee are affected. This blog explains in detail how the disease develops, which symptoms are typical, and why in the end stage often only a prosthesis (hip-THR or knee-THR) helps.
What does secondary osteoarthritis mean in rheumatism?
Under Arthrosis is understood as the wear of the joint cartilage. In primary arthrosis, age and overloading are the main factors. In secondary arthrosis, however, another underlying disease is the cause.
The Rheumatoid Arthritis is a chronic inflammatory autoimmune disease that leads to destruction of the joint synovium, cartilage and bone. From the persistent inflammation, over years a severe damage of the joints develops. This combination of inflammatory rheumatism and degenerative wear clearly distinguishes secondary arthrosis from primary arthrosis.
How does osteoarthritis develop through Rheumatoid Arthritis?
Inflammation as a trigger
The synovial membrane is permanently inflamed and releases enzymes that break down cartilage tissue.
Bone damage and erosions
In rheumatism, the bone edges are literally "eaten away". As a result, the joint loses stability.
Malalignment and instability
Damaged ligaments and bones lead to varus or valgus malalignment, which puts additional stress on the cartilage.
Combination of inflammation and wear
It is typical that patients both Entzündungsschmerzen as well as Arthroseschmerzen have – a particularly burdensome combination.
Hip joint - secondary osteoarthritis in rheumatism
Symptoms
- Groin pain that can radiate to the leg
- Resting pain and load-bearing pain
- Limited mobility, especially internal rotation
- Progressive leg length discrepancy
Consequences
The hip arthrosis in Rheumatoid arthritis often progresses faster than in primary arthrosis. Affected individuals lose their mobility early and require aids.
Knee joint - secondary osteoarthritis in rheumatism
Symptoms
- Pain when walking, standing up or climbing stairs
- Recurring swelling due to synovitis
- Axial deviations (X- or O-legs)
- Significant movement restrictions
Special feature
In the knee misalignments are often strongly pronounced, which makes surgical treatment more difficult.
When is an endoprosthesis (hip replacement, knee replacement) necessary?
If conservative therapies such as physiotherapy, medication or injections are no longer sufficient, this is referred to as the end stage of arthrosis. Typical signs are:
- Persistent pain, even at rest
- Massive limitation in everyday life
- Radiologically detectable joint destruction
- Malalignment and instability
In this phase only a künstliches Gelenk (hip replacement or knee replacement).
Special features in surgeries of rheumatic patients
Patients with rheumatoid arthritis differ from arthrosis patients without rheumatism:
- Bone quality: Often osteoporosis → decision for cemented prostheses
- Soft tissues: Weakened capsule and ligaments require special surgical techniques
- Medications: Immunosuppressants increase the infection risk → close coordination with rheumatology
- Complication risks: Wound healing disorders and infections are more common than in primary osteoarthritis
Results after hip and knee replacement in rheumatism
Despite the challenges, studies show:
- Pain decreases significantly after a prosthesis
- Mobility and quality of life improve
- Risks are slightly increased, but can be minimized in specialized centers
Post-treatment and rehabilitation
The rehab after a prosthesis must be individually adapted for rheumatism:
- Early mobilization to prevent muscle atrophy
- Adapted training due to multi-joint involvement
- Close rheumatological monitoring
- Special wound checks due to increased risk of infection
Why specialized centers are important
Patients with secondary osteoarthritis need experienced surgeons who know the specifics of Rheumatoid arthritis These include:
- Experience with complex cases
- Availability of special implants
- Interdisciplinary collaboration with rheumatologists
- Individually adapted rehabilitation
Frequently Asked Questions (FAQ) on secondary osteoarthritis in Rheumatoid Arthritis
1. What is secondary osteoarthritis?
A secondary osteoarthritis develops when another underlying disease – such as the Rheumatoid Arthritis – damages the joint cartilage and the bones. It differs from primary osteoarthritis, which usually arises from age and wear.
2. How common is osteoarthritis in Rheumatoid Arthritis?
Very common. Studies show that almost all patients with long‑term Rheumatism in the course develop a secondary osteoarthritis – especially at hips and knees.
3. What symptoms indicate secondary osteoarthritis?
Typical symptoms are:
- Pain during exertion and at rest
- Joint swelling and stiffness
- Movement restrictions
- Malalignment such as X- or O-legs
4. Why are the hip and knee particularly affected?
These großen joints bear the entire Körperweight. In Rheumatism they are zusätzlich heavily stressed by Entzündungen and misalignments.
5. How does osteoarthritis in rheumatoid arthritis differ from normal osteoarthritis?
The sekundäre Arthrose progresses faster and combines Entzündungsschmerzen with Verschleißschmerzen. This makes it especially burdensome.
6. What therapies are helpful in the early stage?
- Medications against inflammation (rheumatoid therapy, painkillers)
- Physiotherapy and exercise therapy
- Assistive devices such as orthotics or walking aids
- Joint-friendly sports (e.g. swimming, cycling)
7. When is an artificial joint necessary?
If the pain is persistent, mobility is severely restricted and conservative therapies no longer help, it is a Hip or knee prosthesis the only option.
8. Are surgeries riskier for patients with rheumatism?
Yes, due to osteoporosis, weakened soft tissues and medication, the risk for infections and wound healing complications slightly higher. In specialized centers these risks can, however, be minimized.
9. Which prostheses are suitable for rheumatism?
Often cemented prostheses recommended, as bone quality may be reduced. Modern implants can be individually adapted to the joint situation.
10. How long does an artificial joint last in patients with rheumatism?
Even in Rheumatoid Arthritis Hüft- and knee prostheses usually last many years. Modern materials are service lives of 15–20 years and more possible – provided that aftercare is optimal.
11. How does rehabilitation proceed after a prosthesis in rheumatism?
The rehabilitation is individually adapted. Important are:
- Gentle early mobilization
- Training of multiple joints, as often not just one joint is affected
- Close monitoring by orthopedics and rheumatology
12. Why should one have surgery in a specialized center?
Because there is experience with complex rheumatic Fällen. The ENDOPROTHETICUM Rhein-Main under Prof. Dr. Kutzner offers, for example:
- Individual prosthesis planning
- Special surgical techniques for rheumatism patients
- Interdisciplinary collaboration with rheumatologists
The ENDOPROTHETICUM Rhein-Main – expertise in rheumatism and arthrosis
Under the leadership of Prof. Dr. med. Karl Philipp Kutzner the ENDOPROTHETICUM Rhein-Main is specialized in Hüft- and knee endoprosthetics – also for complex Fällen such as secondary Arthrose due to Rheuma.
Special advantages for patients:
- Modern surgical techniques (e.g., short-stem hip prostheses, modular knee implants)
- Tailored rehabilitation programs
For patients with Rheumatoid arthritis is this the optimal care in the end stage of osteoarthritis.
Conclusion
Secondary arthrosis in rheumatism is a complex clinical picture that particularly affects the hip and knee joints. The combination of inflammation and wear leads quickly to the final stage. Conservative therapies can slow down the process, but not stop it. In the final stage, endoprosthetics of the hip or knee offers the only permanent solution.
Thanks to modern implants, precise surgical planning and specialized centers such as the ENDOPROTHETICUM Rhein-Main under Prof. Kutzner patients with rheumatoid arthritis can also today, with secondary osteoarthritis, lead a pain‑free and active life.
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