Secondary Coxarthrosis (Hip Arthrosis) in Hip Dysplasia

ENDOPROTHETICUM Rhein-Main / Prof. Dr. med. K.P. Kutzner

How does hip osteoarthritis (coxarthrosis) develop from hip dysplasia?

Hip dysplasia is a common congenital malformation of the hip joint, which can lead to significant problems if left untreated and eventually to secondary coxarthrosis (hip osteoarthritis). This article explains the causes, symptoms, diagnostic procedures, and treatment options for hip dysplasia. Learn why early diagnosis and treatment are crucial and how modern medical approaches can improve the quality of life for those affected. It also discusses secondary coxarthrosis in detail, its symptoms, and treatment options.


What is hip dysplasia?

Hip dysplasia refers to a malformation of the hip joint in which the hip socket is not deep enough to fully enclose the femoral head. This malposition leads to an unstable connection between the hip socket and femoral head, resulting in uneven stress on the joint and potentially causing long-term damage. Hip dysplasia often occurs in newborns and is more common in girls than in boys.


Anatomy of the hip joint

The hip joint is a ball-and-socket joint consisting of the femoral head and the acetabulum. The femoral head is the spherical upper part of the femur that fits into the acetabulum of the pelvis. This construction allows for a wide range of motion and stability of the joint. In hip dysplasia, the acetabulum is often too shallow to securely hold the femoral head, leading to instability and increased wear on the joint cartilage.


Causes of Hip Dysplasia

The exact causes of hip dysplasia are not fully understood, but various factors contribute to its occurrence:

Genetic Factors

A familial accumulation suggests that genetic factors play a role. If a parent or sibling is affected by hip dysplasia, the risk for the child to also develop it increases.

Birth position

Babies in breech position have a higher risk of hip dysplasia. This position can increase the pressure on the fetus's hips and lead to malposition.

Sex

Girls are more frequently affected than boys. This could be due to hormonal differences that affect the connective tissue.

Environmental factors

A cramped position in the womb or a lack of amniotic fluid can increase the risk. Also, swaddling infants with straightened legs can promote the development of hip dysplasia.


Symptoms of hip dysplasia

The symptoms of hip dysplasia can vary and are often dependent on the patient's age:

In newborns and infants

  • Asymmetric skin folds: Uneven skin folds on the thighs can indicate hip dysplasia.
  • Limited mobility: Difficulty spreading the legs or limited mobility in the hip joints.
  • Clicking or Clunking: An audible 'click' or 'clunk' when moving the hips can be a sign of instability.

In older children

  • Limping: A noticeable limp may indicate that hip dysplasia is present.
  • Leg length discrepancy: Differences in leg length can indicate uneven stress on the hip joint.
  • Limited mobility: Difficulty bending or rotating the hip.

In adults

  • Pain: Pain in the groin or hip area, especially after physical activity.
  • Stiffness: Stiffness and limited mobility of the hip joint.
  • Arthritis: Signs of premature arthritis in the hip joint.


Diagnosis of Hip Dysplasia

The diagnosis of hip dysplasia is made by a combination of clinical examination and imaging procedures:

Clinical examination

The doctor checks the mobility and stability of the hip joint, often using special tests such as the Ortolani and Barlow tests. These tests help to detect instabilities or misalignments of the hip joint.

Ultrasound

In newborns and infants, ultrasound is the preferred diagnostic tool as it provides a detailed representation of the joint. Ultrasound is particularly helpful in assessing the depth of the acetabulum and the position of the femoral head.

X-ray

In older children and adults, X-rays are often used to assess the exact shape and position of the hip bones. X-rays can also show signs of arthritis or other joint changes.


Treatment options for hip dysplasia

The treatment of hip dysplasia depends on the patient's age and the severity of the malformation:

Conservative treatment

  1. Pavlik harness: In infants, a Pavlik harness is often used, which holds the hips in an optimal position and promotes normal growth. This harness is a soft, flexible splint that holds the baby's legs in a "frog position", which supports the correct alignment of the hips.
  2. Abduction braces and splints: These aids hold the hips in a stable position and enable the correct development of the joint. They are particularly useful for older infants and toddlers.

Surgical treatment

  1. Osteotomy: This procedure corrects the alignment of the hip bones to achieve a better fit between the femoral head and the acetabulum. In an osteotomy, the bone is cut and repositioned to optimize the load on the joint.
  2. Total Hip Replacement (THR): In severe cases or in older patients, replacement of the hip joint with a prosthesis may be necessary. A THR can relieve pain and improve mobility by replacing the damaged joint with an artificial one.


Prevention and early detection

Early detection is crucial to achieve the best treatment outcomes. Regular check-ups in newborns and infants can help to detect and treat hip dysplasia at an early stage. Parents should watch for signs such as asymmetrical skin folds, limited mobility, and unusual noises when moving the hips, and consult a pediatrician if they suspect anything.


Lifestyle and self-help

Patients with hip dysplasia can improve their quality of life through certain lifestyle changes and self-help measures:

Weight control

Maintaining a healthy body weight can reduce the strain on the hip joint and decrease the risk of osteoarthritis. Excess weight increases the pressure on the joints, which can lead to faster wear and tear.

Physical therapy

Targeted exercises can strengthen the muscles, improve joint mobility, and alleviate pain. Physiotherapy can also help improve posture and movement patterns.

Ergonomic Adjustments

Adjusting the workplace and home environment can help reduce the strain on the hips. Ergonomic chairs, properly adjusted desks, and comfortable beds can make a big difference.

Pain relief

Medications such as pain relievers and anti-inflammatory medications can help alleviate acute symptoms. Heat or cold therapy can also contribute to pain relief.


Research and future prospects

Research on hip dysplasia and its treatment options is continually advancing. New diagnostic methods, improved surgical techniques, and innovative therapeutic approaches contribute to improving the quality of life for those affected. The development of new materials and prosthetics, as well as the use of robotics and computer assistance in surgery, offer promising possibilities for the future.

Genetic Research

Genetic studies help to better understand the causes of hip dysplasia and identify potential risk factors. This could lead to preventive measures and targeted treatments in the future.

Regenerative Medicine

Regenerative medicine is researching ways to repair or regenerate damaged cartilage and other tissues in the hip joint. Stem cell therapies and other innovative approaches could significantly expand treatment options.


Summary

Hip dysplasia is a congenital malformation of the hip joint, which can lead to serious complications if left untreated. One of the most common consequences is secondary coxarthrosis, a degenerative joint disease that arises from the uneven wear of the articular cartilage. Understanding the connections between hip dysplasia and secondary coxarthrosis is therefore of great importance.


The following section provides an overview of secondary coxarthrosis (hip osteoarthritis), its symptoms, diagnostic methods, and treatment options.


Causes of secondary coxarthrosis in hip dysplasia

Secondary coxarthrosis develops as a result of uneven stress and wear on the hip joint. In hip dysplasia, the joint surface is unevenly distributed, leading to increased pressure on certain areas of the articular cartilage. Over the years, this excessive pressure can damage the cartilage and lead to inflammation, pain, and ultimately, cartilage degeneration. These degenerative changes characterize secondary coxarthrosis.


Mechanisms of the development of secondary coxarthrosis due to hip dysplasia

Introduction

Hip dysplasia, a congenital malformation of the hip joint, can lead to secondary coxarthrosis if left untreated. This form of arthrosis is a degenerative joint disease characterized by the wear and tear and destruction of the cartilage in the hip joint. The following explains the mechanisms by which hip dysplasia can lead to the development of secondary coxarthrosis.


Anatomical basics of hip dysplasia

In hip dysplasia, the acetabulum is too shallow or malformed, so that the femoral head is not sufficiently stabilized. This leads to uneven stress and increased wear on the joint surfaces. The inadequate coverage of the femoral head by the acetabulum can cause the following problems:

  1. Hip joint instability: The femoral head can easily slip out of the hip socket (subluxation) or be completely dislocated (luxation).
  2. Uneven pressure distribution: The pressure on the femoral head is unevenly distributed, leading to excessive stress on certain areas of the joint.


Mechanisms of cartilage wear

The unstable and unevenly loaded hip socket leads to several biomechanical changes that favor the development of secondary coxarthrosis:

  1. Increased mechanical stress: The uneven distribution of load on the femoral head leads to increased pressure on specific areas of the articular cartilage. This increased pressure can cause micro-cracks and damage to the cartilage, which worsen over time.
  2. Wear of the articular cartilage: Due to the constant instability and friction between the femoral head and acetabulum, the protective articular cartilage is worn away, leading to pain and inflammation.
  3. Changes in synovial fluid: Due to mechanical stress and inflammatory processes, the composition of the synovial fluid changes, impairing the lubrication and nutrition of the cartilage.


Inflammatory processes

Mechanical damage to the articular cartilage leads to an inflammatory reaction in the hip joint. These inflammatory responses further contribute to cartilage damage and exacerbate the degenerative process:

  1. Release of inflammatory mediators: When damage occurs to the articular cartilage, inflammatory mediators such as cytokines and enzymes are released, accelerating the breakdown of cartilage.
  2. Synovitis: Inflammation of the synovial membrane leads to swelling and increased production of joint fluid, causing additional pain and limited mobility.


Bone changes

In the course of hip dysplasia and the resulting coxarthrosis, changes occur in the bones of the hip joint:

  1. Osteophyte formation: Due to the ongoing mechanical stress, bony growths (osteophytes) form at the edges of the joint. These osteophytes can further restrict mobility and cause pain.
  2. Subchondral sclerosis: The bone beneath the damaged cartilage becomes denser (subchondral sclerosis) and less shock-absorbing, contributing to further deterioration of the joint.


Clinical symptoms of secondary coxarthrosis

The mechanisms described above lead to the typical symptoms of secondary coxarthrosis:

  1. Pain: Initially, the pain occurs under load, later also at rest. Typically, the pain is localized in the groin, thigh or buttocks.
  2. Stiffness: The mobility of the hip joint is limited, especially after periods of rest (morning stiffness).
  3. Movement restrictions: Patients have difficulty performing everyday movements such as bending, climbing stairs, or putting on shoes.


Diagnosis of secondary coxarthrosis in hip dysplasia

The diagnosis is based on a combination of clinical examination, medical history, and imaging techniques:

  1. Clinical examination: The doctor checks the mobility and stability of the hip joint and looks for signs of pain or movement restrictions.
  2. X-ray: X-ray images show changes in joint space width, osteophytes, and subchondral sclerosis, indicating advanced coxarthrosis.
  3. MRI: An MRI can provide detailed images of the soft tissues and cartilage and helps assess the extent of cartilage damage and inflammation.


Treatment of secondary coxarthrosis in hip dysplasia

The treatment aims to alleviate pain, improve joint function, and slow the progression of the disease:

Conservative measures

  1. Physiotherapy: Targeted exercises to strengthen the muscles and improve joint mobility.
  2. Pain medication: Use of painkillers and anti-inflammatory medications to relieve symptoms.
  3. Weight management: Weight reduction to relieve the hip joint.

Surgical interventions

  1. Osteotomy: Corrective surgeries to improve joint mechanics and reduce the load on the joint.
  2. Hip replacement: In advanced cases, a complete hip replacement may be necessary to relieve pain and improve mobility.

Conclusion

Hip dysplasia leads to the development of secondary coxarthrosis through a combination of mechanical, inflammatory, and bony changes. Early diagnosis and adequate treatment are crucial to maintaining the quality of life of those affected and slowing the progression of the disease.


Symptoms of secondary coxarthrosis

The symptoms of secondary coxarthrosis in hip dysplasia can vary, but often include:

  • Pain: Initially, pain often occurs after physical exertion, and in advanced stages, also at rest.
  • Limited Mobility: Patients often report stiffness in the hip joint, especially after prolonged sitting or lying down.
  • Joint noises: Grinding or cracking noises in the hip joint can indicate cartilage damage.
  • Joint deformity: In advanced stages, visible changes and malalignments of the hip joint can occur.

Diagnosis

The diagnosis of secondary coxarthrosis in hip dysplasia is made through a combination of clinical examination and imaging techniques:

  • Clinical examination: The doctor checks the mobility and pain sensitivity of the hip joint.
  • X-rays: These show the shape and depth of the acetabulum as well as any changes to the femoral head.
  • Magnetic Resonance Imaging (MRI): This method provides detailed images of the cartilage and soft tissues and helps assess the extent of the damage.


Treatment options

The treatment of secondary coxarthrosis in hip dysplasia aims to alleviate pain, improve the function of the hip joint, and slow the progression of the disease. Depending on the severity of the symptoms and the extent of the joint damage, different therapeutic approaches are used:

Conservative treatment

  1. Physiotherapy: Exercises to strengthen the muscles and improve joint mobility can help reduce the load on the hip joint.
  2. Medication therapy: Pain relievers and anti-inflammatory medications (NSAIDs) can alleviate acute symptoms.
  3. Assistive devices: Orthopedic insoles or walking aids can reduce the strain on the hip joint.

Surgical Treatment

  1. Arthroscopy: In early stages of coxarthrosis, a minimally invasive arthroscopy can be performed to remove damaged tissue and improve joint function.
  2. Osteotomy: In this operation, the hip bone is realigned to optimize the load distribution in the joint and reduce wear.
  3. Total hip replacement (THR): In advanced stages of coxarthrosis, replacement of the hip joint with an artificial joint may be necessary.


Prevention and early detection

Early detection and treatment of hip dysplasia are crucial to prevent the development of secondary coxarthrosis. Regular check-ups in infants and young children, as well as timely treatment of diagnosed hip dysplasia, can significantly reduce the risk of complications. Parents should watch for signs of hip dysplasia, such as asymmetrical skin folds or limited mobility of the hips, and consult a pediatrician if suspected.


Conclusion

Secondary coxarthrosis (hip osteoarthritis) in hip dysplasia is a common complication that arises from uneven stress and wear on the hip joint. Early diagnosis and treatment of hip dysplasia are crucial to minimize the risk of secondary coxarthrosis. Through a combination of conservative and surgical treatment approaches, pain can be alleviated and the function of the hip joint improved. Patients should undergo regular examinations and seek medical advice at the first signs of hip dysplasia or coxarthrosis to avoid long-term damage.

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